Clinical predictors of gleason score upgrading

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Upgrading of Gleason score and prostate volume: a clinicopathological analysis.

OBJECTIVE To more clearly elucidate the association between prostate volume and Gleason score (GS) upgrading. PATIENT AND METHODS We reviewed 451 patients with prostate cancer with a GS of 6 on biopsy, who underwent radical prostatectomy without neoadjuvant treatment. As a preoperative variable, we assessed the independent effect of prostate volume on GS upgrading. To evaluate the association...

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Factors predicting Gleason score 6 upgrading after radical prostatectomy

OBJECTIVES Prostate cancer Gleason score 6 is the most common score detected on prostatic biopsy. We analyzed the clinical parameters that predict the likelihood of Gleason score upgrading after radical prostatectomy. METHODS The study population consisted of 241 patients who underwent radical retropubic prostatectomy between Feb 2002 and Dec 2007 for Gleason score 6 adenocarcinoma. The influ...

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Patient risk stratification using Gleason score concordance and upgrading among men with prostate biopsy Gleason score 6 or 7.

PURPOSE To define the impact of discordant Gleason sum (GS) between prostate biopsy (Pbx) tissue and radical prostatectomy (RP) specimen among men initially diagnosed with Gleason 6 or 7 prostate adenocarcinoma. MATERIALS AND METHODS We evaluated patients diagnosed with GS 6 or 7 and treated primarily with RP. We defined the frequency of GS discordance between Pbx and RP pathology reports. We...

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The probability of Gleason score upgrading between biopsy and radical prostatectomy can be accurately predicted.

The objective of this study was to test the external validity of a previously developed nomogram for the prediction of Gleason score upgrading (GSU) between biopsy and radical prostatectomy (RP). The study population consisted of 973 assessable patients treated with RP at a tertiary care institution. The accuracy of the nomogram was quantified with the receiver operating characteristics curve-d...

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Is Small Prostate Volume a Predictor of Gleason Score Upgrading after Radical Prostatectomy?

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ژورنال

عنوان ژورنال: Cancer

سال: 2007

ISSN: 0008-543X,1097-0142

DOI: 10.1002/cncr.22712